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If you become pregnant and are taking Prilosec®, you should tell your doctor right away. There has not been enough research into the effects of Prilosec® during pregnancy to know how safe it is. It is known, however, that the medication shows up in breast milk.

If you are taking Prilosec® and are breastfeeding, your doctor may want to take you off of the medication until you finish breastfeeding your baby.

What is Prilosec®?

Prilosec® is in a class of drugs called proton pump inhibitors (PPIs). Proton pumps are cells in the stomach that produce acid to help digest food. The medications work by inhibiting the activity of the acid-producing cells.

When the stomach’s proton pumps are producing too much acid, Prilosec® is used to treat:

• Persistent heartburn
• Gastroesophageal reflux disease (GERD)
• Ulcers of the lining of the stomach and small intestine
• Erosive esophagitis (severe inflammation of the esophagus)

It is also used long term to treat conditions in which the stomach produces too much acid. These include Zollinger-Ellison syndrome, multiple endocrine adenomas, which are benign tumors and systemic mastocytosis, which are cancerous cells.

The medication can also be used in combination with antibiotics to treat stomach ulcers caused by the bacteria H. pylori.

Prilosec® comes in both prescription and nonprescription formulations.

Prilosec® Side Effects

Side effects of PPIs include headache, diarrhea, stomach pain, gas, nausea and vomiting. Serious Prilosec® side effects that indicate an allergic reaction is occurring include hives, difficulty breathing, and swelling of the face, tongue or lips. If any of these latter side effects occur, patients should go to the emergency room or call 911.

Other, unexpected side effects of PPIs have been uncovered recently. In an analysis of seven epidemiological studies, the Food and Drug Administration (FDA) found data that showed Prilosec® and other PPIs were associated with an increased risk of the following:

• Hip fractures
• Spine fractures
• Wrist fractures

In May 2010, the FDA released an advisory, warning patients and health care professionals of this possibility. These fractures have been noticed in patients taking both the prescription and over-the-counter forms of the drug. As part of the advisory, the FDA reported it was requiring a change in the labels of PPIs, warning of these dangers.

For more information about Prilosec® and the potential dangers, contact our Prilosec® attorneys.