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PPA- or Phenylpropanolamine- is an ingredient that has been included in over-the-counter (OTC) and prescription cold remedy and appetite suppressant medications for over fifty years. PPA is a vaso-constrictor, meaning that it causes the blood vessels to narrow so that less blood flow is possible. This constriction causes an increase in blood pressure and in some cases can cause the blood vessel to rupture and hemorrhage. PPA injury occurs when drugs containing this product cause hemorrhagic stroke, or “bleeding of the brain.”
Evidence of this PPA injury was confirmed by a study done at Yale University. This study found that women are at a higher risk for having a serious PPA injury. Women between the ages of 18 and 49 were sixteen times more likely to suffer a hemorrhagic stroke after only three days of taking PPA drugs compared to those who did not take these medications. Of all patients who suffer a hemorrhagic stroke, those taking PPA medications were 50 percent more likely to develop hemorrhaging, or excessive bleeding, of the brain. This was especially true in women who were taking PPA-containing appetite suppressants alone or in combination with cold and cough medications.
The symptoms of the PPA injury hemorrhagic stoke include headache, nausea, vomiting, stiffened neck, eye problems, body rigidity, confusion and altered mental states. In more severe PPA injury cases the stoke victim can actually enter into a coma or die.
In November of 2000, the Federal Drug Administration (FDA) recalled all over the counter PPA-containing products. In light of substantial PPA injury evidence, the FDA also urged companies to voluntarily discontinue the manufacturing of PPA-containing medicines and requested that they stop marketing these products. They also issued a public health advisory to warn consumers of the PPA injury risks associated with these products.
Since PPA injury evidence was confirmed and OTC products were recalled by the Federal government, cold remedy and appetite suppressant drug manufacturers have begun pulling their PPA products and reformulating safer, PPA-free alternatives. These products are still in the process of being pulled from the market and reformulated, therefore it is important to check the labeling information on any OTC product you purchase to avoid taking PPA-containing drugs and potentially suffering a PPA injury.
If you suspect or know that you have been a victim of a PPA injury, you have the legal right to seek compensation for your damages. Under tort, or personal injury law, you may be eligible to collect damages from the PPA drug manufacturers for your medical costs, loss of wages, pain and suffering, and any permanent or partial disability you have incurred because of a PPA injury.
In November 2000, the FDA asked companies using PPA (phenlypropanolamine) in their cold products to voluntarily take the products off the market because of possible health risks, including links with hemorrhagic stroke in first time female users. Now,...
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