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October 1, 2003
"Assessing Brain Iinjury Damage Can Be Difficult"
It can be very difficult to immediately evaluate and determine the amount
of damage suffered in a brain injury. Every year, nearly 2 million Americans
suffer a traumatic brain injury, resulting in 52,000 deaths. The impact
brain injuries can have varies from mild to deadly but can be tough to ascertain
the level of damage.
September 30 , 2003
"New brain injury drug on fast track status"
The FDA recently awarded Pharmos’ traumatic brain injury drug a fast
track status. The traumatic brain injury treatment is intended to treat
secondary neuroprotective brain damage following the injury. Often times,
there can be a secondary injury that occurs after the initial trauma has
been suffered that can be extremely damaging.
According to Pharmos, the U.S. market of patients with traumatic brain injury is estimated to be more than $500 million, with international market potential in excess of $1 billion. Nearly 2 million American suffer a traumatic brain injury every year.
September 25 , 2003
"New brain injury treatment being studied"
Scientists have been discussing what is being considered the world’s
first clinical trial to use the hormone progesterone as a treatment for
moderate to severe traumatic brain injury. Every year, 50,000 Americans
die because of a traumatic brain injury and 80,000 more Americans become
disabled. Some brain injury treatments can include barbiturates, mannitol,
and surgery, but these methods are last-resort and do not always work.
Daily life can become severely disrupted because of a brain injury and tasks such as concentrating or memory can become problematic. In animal studies, progesterone was able to improve memory and cognitive thinking skills after suffering a brain injury. The rats had less brain swelling and were able to better recover when treated shortly after the brain injury.
The progesterone was able to moderate the brain injury inflammation that can lead to dangerous head swelling after a brain injury. After a traumatic brain injury is suffered, damaging chemicals called free radicals appear to be slowed and sometimes blocked by the use of progesterone. The secondary injury after the initial brain injury trauma is what can cause increases in brain injury size and lead to death, but progesterone brain injury treatment seems to protect the brain from nerve, neuron, and other brain cell breakdown.
So far, any attempt for an effective traumatic brain injury (TBI) drug has failed. Pharmos said that its experimental drug dexanabinol, while only partially preventing cognitive problems in patients undergoing heart surgery in a midstage stud...
Every year, about 1.5 million Americans suffer a traumatic brain injury (TBI). A TBI is caused by impact of an outside force to the head that can break the skull bone and damage the underlying brain tissue, or a brain injury can be suffered when th...