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Heparin allergic reactions and heparin-linked fatalities prompted the Feb. 2008 recall of most of the heparin products distributed in the United States by Baxter International, Inc. Heparin allergic reactions may involve the following symptoms:

• A rapid drop in blood pressure
• Nausea and vomiting
• Increased heart rate
• Swelling around the mouth
• Difficulty breathing
• Sweating

Nineteen Deaths Linked to Heparin Allergic Reactions

Heparin allergic reactions may be caused by a 'counterfeit' heparin-like substance that mimics heparin but is not exactly the same. Nineteen deaths in the U.S. have been attributed to heparin allergic reactions since Jan. 1, 2007, and about 750 non-fatal adverse reactions were reported in the same period to the U.S. Food and Drug Administration (FDA).

Heparin from China

Baxter and the FDA recently confirmed that a contaminant was present in some of the nine lots of recalled heparin, and that a contaminant was found in the active ingredient used in most of the heparin provided by Baxter. A Wisconsin company, Scientific Protein Laboratories LLC (SPL) provides the heparin to Baxter. SPL obtains heparin from its facility in Changzhou, China.

Heparin Allergic Reactions Reported in Germany Too

About 100 cases of heparin allergic reactions were recently reported to health authorities in Germany, and a preliminary investigation revealed that the heparin involved in these reactions was from a German company, Rotexmedica, that also gets its heparin from Chinese facilities (although the facilities are not the same ones as used by Baxter).

The fact that heparin allergic reactions are being traced to a variety of plants in China suggests that a contamination problem is present at a point further up the supply chain.

Most of the World's Heparin Is from China

A major portion of the heparin used throughout the world originates in China, where the pigs whose intestinal lining provides the source of heparin are raised and slaughtered. The demand for heparin in the U.S. is greater than what can be supported by the number of existing pig farms in the U.S. China exports heparin to 41 other countries and regions in addition to the U.S., and it exports the greatest amount of its heparin to Germany.

Learn More about Heparin Allergic Reactions

If a heparin allergic reaction has harmed you or your loved one, you have legal rights. Get more information from a heparin lawyer in your area today.

"Heparin Linked Deaths Continue to Pile"

After months of investigation, the U.S. Food and Drug Administration has definitively tied three patient deaths to contaminated heparin.

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"Devices Coated with Carmeda BioActive Recalled"

Medical device maker Medtronic has issued a voluntary recall of heparin-coated bypass equipment, including pumps, reservoirs and blood oxygenators. The company said the recall is a pre...

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"Families Testify for Loved Ones Harmed by Heparin"

The families of people who died from contaminated heparin injections testified before Congress last week, expressing anger and grief over manufacturing and regulatory safety failures.

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