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More reports keep coming to light of a possible connection between fractures of the femur (thigh bone) and bisphosphonates. Fosamax® is in the class of drugs called bisphosphonates that are used to treat osteoporosis.

Fosamax® and Femur Fractures

A task force of the American Society for Bone and Mineral Research on Sept. 14, 2010, published a report online of atypical fractures of the femur (thigh bone) and a connection to bisphosphonates, such as Fosamax®.

The task force found that

• 291 of 310 (94 percent) patients with atypical femur fractures had taken the drugs
• Most of the patients had taken the medications for longer than five years

The task force recommended that the label on the drugs be changed to warn doctors and patients of the possibility of atypical femoral fractures and that they might be present in both legs.

The U.S. Food and Drug Administration (FDA) also published an online report on the same day, saying that there was a possibility of increased risk of certain types of fractures of the thigh bone in patients using bisphosphonates for a long period of time.

On Sept. 15, 2010, the Journal of Clinical Endocrinology & Metabolism published an online report about an analysis of cumulative Fosamax® use and the long-term absolute risk of femoral fractures. The report concluded that patients taking Fosamax® have a higher risk of fractures of the femur than matched control subjects, but because no large cumulative dose-relationship could be found, the fractures might be due to osteoporosis rather than to Fosamax®.

Various sources are reporting a relationship between use of Fosamax® and structural damage to the bone. Researchers are finding that Fosamax® and similar drugs suppress bone turnover, which is how new bone is formed and old bone is restored. This suppression is what seems to be causing the structural damage.

These findings and discussions of femoral fractures have been discussed in reports by the FDA, The Journal of Bone Joint Surgery, American Volume; Osteoporosis International; Journal Watch General Medicine; Drug Safety; Journal for Bone and Mineral Research; and Orthopedics, among others.

Fosamax® Femur Fracture Lawsuit

If you have taken Fosamax® for more than five years and have experienced a femur fracture, you may be entitled to seek compensation for the pain, suffering and expense you have endured through a Fosamax® lawsuit.

It is in your best interest to contact a Fosamax® lawyer today to discuss your situation in regards to a lawsuit. A qualified Fosamax® attorney can help you seek justice for your injury. For more information or to schedule a case evaluation, call us today at (877) 612-9867.

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