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Darvocet-N 100 is a form of the prescription narcotic pain reliever. The "100" means 100 mg of one of its active ingredients, propoxyphene napsylate. The active ingredients in Darvocet-N 100 are:

• 100 mg of propoxyphene
• 650 mg of acetaminophen

It comes in tablet form.

Darvocet-N 100 dosage

Patients usually take Darvocet-N 100 every four hours and should not take more than 6 tablets a day.

If patients are taking a form of CYP3A4 (a type of enzyme) inhibitor, they should be monitored closely in case adjustments in dosage are needed. Older patients or those who have impaired liver or kidney function may require a lower dose.

Doctors of patients who stop taking Darvocet-N 100 might reduce the dosages slowly and give the medication at longer intervals, in order to reduce the possibility of withdrawal because of the narcotic action of the drug.

Who Should Avoid Taking Darvocet-N

Patients should not take Darvocet N if they:

• Are allergic or hypersensitive to propoxyphene or acetaminophen
• Have significant respiratory depression (if they are unmonitored and resuscitative equipment is unavailable) or acute or severe asthma
• Might have paralytic ileus (a bowel obstruction)
• Drink a significant amount of alcohol or are taking other drugs that depress the central nervous system. Liver toxicity or liver failure and death can result. Caution should be used in prescribing the drug for patients who are also taking sedatives, tranquilizers, muscle relaxants, antidepressants or other CNS depressant medications.
• Are taking other acetaminophen-containing drugs because excess acetaminophen toxicity of the liver can result

On November 19, 2010, the U.S. Food and Drug Administration recalled Darvocet, as well as Darvon (propoxyphene without acetaminophen.) The FDA and Darvocet's manufacturer announced the withdrawal of propoxyphene from the market. Darvocet is made by Kentucky-based Xanodyne Pharmaceuticals.

A spokesman for the Public Citizen's Health Research Group. Dr. Sydney Wolfe, said the ban was too "little, too late."

Britain banned drugs that contained propoxyphene in 2005. The European Medicines Agency recommended the drug be gradually removed from the European Union market in 2009.

Other names under which propoxyphene is sold include Dolene, Propacet 100, Wygestic, SK-65, SK-65 APAP, Trycet Genagesic, E-Lor, and Balacet.

Contact a Darvocet-N 100 Attorney

If you or someone you love has had heart problems while taking Darvocet-N 100, or perhaps even had a heart attack or died, you can benefit from the services of a Darvocet-N 100 attorney. You or they should be reimbursed for the pain and suffering caused by this medication. Your initial consultation with a Darvocet-N 100 lawyer is free.

"Darvocet® and Darvon® Recalled for Fatal Heart Side Effects"

Xanodyne Pharmaceuticals, maker of the painkillers Darvocet® and Darvon® has pulled both drugs from U.S. m...

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