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A review of data from numerous clinical studies showed Darvocet® causes harmful and potentially fatal changes in the electrical activity of the heart. The changes were found on patients’ electrocardiograms.

Darvocet® was recalled in November 2010 because of the high risk of heart-related death as well as death by accidental overdose.

Darvocet® Arrhythmias

Four types of dangerous and possibly lethal changes were found in the heart rhythms of Darvocet® patients:

• Tachycardia or heart beats that were too rapid, meaning more than 100 beats per minute
• Bradycardia or heart beats that were too fast, meaning less than 60 beats per minute
• Irregular heart beats
• Origination of the heartbeat in the wrong location in the heart muscle

Other Heart Conditions Linked to Darvocet®

Darvocet® is also linked to an increased risk of:

• Cardiac arrest — This is failure of normal circulation of the blood because the heart stops contracting effectively. This is an emergency situation that must be treated immediately.
• Heart attack — or myocardial infarction. This is permanent damage to the heart muscle caused by lack of adequate blood flow. It results in the death of some heart muscle cells.  It must be treated as a medical emergency.
• Congestive heart failure — This condition occurs when the heart cannot pump enough blood to meet the needs of the tissues and organs of the body.

The dangers to the heart are the basis for the November 2010 recall of Darvocet®, Darvon® and related generic drugs from the market by the U.S. Food and Drug Administration (FDA).   Xanodyne, the drugs’ manufacturer and the FDA made the announcement jointly.

“The FDA is pleased by Xanodyne’s decision to voluntarily remove its products from the U.S. market,” said Dr. John Jenkins, director of the Office of New Drugs in the FDA’s Center for Drug Evaluation and Research.

What Causes Darvocet® Heart-Related Death?

The drugs’ main active ingredient, propoxyphene or dextropropoxyphene, is the culprit. An opioid analgesic for mild to moderate pain, propoxyphene was found to be causing dangerous and potentially lethal changes to the electrical activity of patients’ hearts as seen on electrocardiograms.

“These new heart data,” according to Dr. Jenkins, “significantly alter propoxyphene’s risk-benefit profile. The drug’s effectiveness in reducing pain is no longer enough to outweigh the drug’s serious potential heart risks.”

Propoxyphene is also the active ingredient in Darvon®, which was also included in the recall. The FDA is also asking manufacturing companies who make the generic versions to remove their drugs from the market as well.

Talk to a Darvocet® Lawyer

If your loved one died because of heart trouble and he/she has a history of taking Darvocet® for pain, you might have a wrongful death claim. Contact a Darvocet® heart side effect lawyer today to find out if you are eligible for financial compensation.

"Darvocet® and Darvon® Recalled for Fatal Heart Side Effects"

Xanodyne Pharmaceuticals, maker of the painkillers Darvocet® and Darvon® has pulled both drugs from U.S. m...

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