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Byetta, an injectable medication prescribed in the treatment of type-2 diabetes, can improve control of blood sugar levels by helping the pancreas produce insulin more efficiently.

Since the Food and Drug Administration (FDA) approved the Byetta drug in April 2005, various studies have shown that this medication is known to cause a range of mild to serious side effects. However, not all of these Byetta side effects are negative, as some patients experience and benefit from the weight loss.

What Causes Byetta Weight Loss?

Although researchers are still investigating precisely how Byetta causes patients to lose weight, some speculate that Byetta weight loss results from:

• food traveling from the stomach to the small intestine at a slower rate
• Byetta patients feeling "fuller" faster and longer
• patients consuming less food during meals and throughout the day

Byetta Weight Loss Study

A number of clinical trials have been conducted to highlight the link between use of Byetta and weight loss, including the following:

• A clinical trial of 537 patients who tested Byetta against insulin found that, on average, Byetta patients lost 5 pounds after 6 months of using Byetta. In contrast, patients taking insulin gained 4 lbs.
• A Byetta weight loss study of 146 patients found that, after two years of using Byetta, they lost an average of 12 pounds. This study also highlighted that patients experienced greater Byetta weight loss the longer they used this drug.

Is Byetta An Appropriate Weight Loss Drug for Non-Diabetics?

The FDA, as well as the makers of Byetta (Amylin Pharmaceuticals and Eli Lilly), emphasize that Byetta should only be prescribed to patients with type-2 diabetes who need help controlling their blood glucose levels.

Although healthcare professionals can legally prescribe Byetta for weight loss use in patients with normal blood sugar levels, insurers typically won't cover the costs of the medication for non-approved patients.

To date, no studies have been conducted regarding use of Byetta as weight loss drug for non-diabetics. Amylin Pharmaceuticals and Eli Lilly report having no plans to pursue such studies.

Byetta Weight Loss Results

Ultimately, various Byetta weight loss studies have found that:

• The greatest Byetta weight loss occurs in patients who are the most overweight when they start taking this medication
• Weight loss will continue at the same rate during the first 2.25 years of taking Byetta as directed
• About 25 percent of Byetta patients experience substantial weight loss
• About 25 percent of Byetta patients experience no weight loss or small weight gain

Healthcare professionals also stress that optimal Byetta weight loss will only occur if it's paired with healthy eating and regular exercise. Of the patients who experience significant Byetta weight loss, most report being motivated to adopt healthier lifestyles upon initially losing a few pounds on Byetta.

For more information about Byetta, its pros and cons, contact our Byetta attorney today.