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Byetta® and depression are linked in many people. The adults with type 2 diabetes who comprise the patient population for Byetta® — a self-administered twice-daily injection — may experience depression for a number of reasons, including:

• significant, long-term nausea due to Byetta® use
• continual diarrhea
• irritability due to low blood sugar (hypoglycemia)
• disappointment in Byetta's® effectiveness
• other medical problems based on diabetes; e.g., blindness, amputation

Diabetes and Depression

According to the American Diabetes Association, over 23 million people in the U.S. (about eight percent of the population) have diabetes. In addition, the prevalence of diabetes increased 13.5% from 2005 to 2007. Although type 2 diabetes is treatable, it can be discouraging to live with the constant and life-long challenges of being diabetic, resulting in mild to severe depression.

Higher Risk of Many Medical Problems

For example, having type 2 diabetes puts a person at higher risk for many medical problems, such as:

• heart disease and stroke — these account for about 65% of deaths in people with diabetes
• high blood pressure — about three-quarters of adults with diabetes have it
• blindness — diabetes is the leading cause of new cases of blindness in adults 20 to 74 years of age
• kidney disease — diabetes is the leading case of kidney failure
• amputation — the rate of amputation for patients with diabetes is ten times higher than for those without it
• dental disease — almost a third of the people with diabetes in the U.S. have severe periodontal disease
• significantly increased risk of sexual dysfunction
• nervous system disease — roughly 60%–70% of people with diabetes have signs of nervous system damage such as impaired digestion or impaired sensation or pain in the feet and/or hands

Knowing of all these risks (let alone dealing with one or more of these medical conditions) can produce depression in people with diabetes. Any added risk of depression linked to Byetta® is a serious concern. An individual with both diabetes and depression should maintain regular contact with his or her physician, and should inform the doctor of the depression as soon as possible.

How to Decrease Nausea Created by Byetta®

In addition to seeking medical care for depression from a healthcare professional, a Byetta® user should not underestimate the effect that constant nausea can have on one's mental state. If nausea from Byetta® is suspected as a major cause of an individual's depression, treating the nausea may well help lift the depression.

"Byetta® May Be Linked to Pancreatitis and Cancer"

University of California, Los Angeles (UCLA) researchers have found that the use of the diabetes medications Byetta® and Januvia® may increase the risk of serious problems with the pancreas. Januvia® and Byetta® are both used to treat t...

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