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Produced by Hoffman-LaRouche, Accutane® is an oral medication that may be prescribed in the treatment of severe acne when other treatments don't work. Accutane is generically known as isotretinoin and is a derivative of vitamin A, meaning it's a retinoid. Despite its current use, however, Accutane was first developed to be part of chemotherapy treatment for brain cancer, pancreatic cancer and other malignancies.

Other Names for Accutane®

Isotretinoin is available under a number of brand names. For oral forms, brand names may include:

• Amnesteem,® by Mylan Pharmaceuticals
• Claravis,® by Barr
• Clarus,® by PremPharm
• Decutan,® by Actavis Totowa
• Isotane,® by Pacific Pharmaceuticals
• Isotret,® by Liva Healthcare Ltd.
• Izotek,® by BlauFarma
• Ortane,® by Genepharm Australasia
• Sotret,® by Ranbaxy

Isotretinoin is also available in topical forms, which are marketed at Isotrex® or Isotrexin®, both of which are produced by Stiefel.

Accutane® Drug Facts

Before starting a course of Accutane®, patients should:

• Discuss their complete medical history with their doctor before starting a course of Accutane®, as this medication can be unsafe for those with a medical (or family) history of mental illness, heart disease, osteoporosis, diabetes, anorexia and/or liver disease.
  
• Enroll in the FDA-mandated program iPLEDGE, which requires women to agree that they understand Accutane® side effects and that they will use two forms of birth control, should they start taking this medication.
  
• Never attempt to get Accutane® via the Internet or any other source that is not iPLEDGE, as this can increase their risk of develop serious Accutane® side effects.

Accutane® has only been legally available via iPLEDGE since March 2006. The medication can only be dispensed to patients once physicians approve their request (after patients have filled out all iPLEDGE forms). Then, doctors can only prescribe a 30-day supply of Accutane® at a given time. Patients who want a refill will need to go through the entire iPLEDGE process again at the time of their refill request.

The precise dose a patient is prescribed, as well as the length of time Accutane® will need to be taken, will depend on the nature and severity of the acne, as well as the patient's weight and height.

Side Effects of Accutane® Drug

Accutane® patients may experience minor, passing and treatable side effects, which may include:

• back and/or joint pain
• dizziness
• drowsiness
• dryness of the skin, mouth, lips and/or nose (which can be marked by skin cracking or peeling)
• itchiness
• irritable bowel syndrome
• nervousness
• skin rash

In the worst cases, Accutane® has been reported to cause number of serious side effects, including:

• alopecia (hair loss)
• depression
• erectile dysfunction (though this is usually accompanied by depression and is, therefore, thought to be a side effect of mental disturbances associated with Accutane)
• inflammatory bowel disease (marked by chronic abdominal pain, diarrhea and/or constipation)
• hepatitis
• pancreatitis (inflammation of the pancreas marked by abdominal pain and/or tenderness)
• psychosis
• severe allergic reaction
• suicidal thoughts or tendencies

Accutane® patients should seek emergency medical care should they develop symptoms of any of the above side effects to prevent irreversible damage and further damage to their health.

Have you or a loved one been seriously injured after taking Accutane®? If so, you should contact an experienced Accutane® attorney (once your health is stable) to learn more about your legal rights. An attorney experienced in handling injury cases involving Accutance will be able to help you recover compensation for your damages.

"Generic versions of Accutane® carry similar risks"

The side effects that are associated with Accutane® are relatively well known, but less attention is typically paid to generic versions of the drug that use the ...

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"Dosage size of Accutane® affects side effects"

A recent study has found that the adverse side effects associated with isotretinoin, the active ingredient in Accutane®, may be reduced if the patient takes smal...

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"Research shows Accutane increases risk of ulcerative colitis"

A recent study published the American Journal of Gastroenterology, isotretinoin, whose brand name is Accutane, can cause a number of inflammatory bowel diseases.

» Read More