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Avandia® side effects have sparked much controversy around use of the medication. Produced by GlaxoSmithKline, Avandia® is an oral thiazolidinedione medication prescribed in the treatment of type-2 diabetes, also referred to as adult-onset diabetes. Avandia® improves the body's control of blood sugar levels by making cells throughout the body more receptive to insulin.

Avandia® is generically known as rosiglitazone and is NOT indicated for treatment of type-1 diabetes, also referred to as juvenile diabetes.

Serious Side Effects of Avandia®

Despite being an effective anti-diabetes medication, however, Avandia® has been reported to cause some rare but serious side effects, including:

• bone fracture (especially in the arms, hands or feet)
• congestive heart failure
• heart attack
• hypoglycemia (dangerously low blood sugar)
• hyperglycemia (dangerously high blood sugar)
• jaundice
• liver dysfunction
• severe allergic reaction
• upper respiratory tract infection

Avandia® patients who sustain such injuries will likely have a legal claim or an Avandia® lawsuit against GlaxoSmithKline and will be entitled to seek a settlement for their injuries and losses.

Symptoms & Doctor Recommendations (Treatment Options)

It's important that Avandia® patients understand the symptoms of serious Avandia® side effects so they know when to seek emergency medical care to prevent further damage to their health.

Symptoms of severe Avandia® side effects may include (but aren't limited to):

• blurry vision
• breathing difficulties
• chest, shoulder and/or arm pain
• confusion and/or dizziness
• easy bleeding and/or bruising
• hives and/or skin rash
• increased hunger, thirst and/or urination
• nausea and/or vomiting
• sweating
• weakness

Upon an official diagnosis of severe Avandia® side effects, doctors will typically recommend some combination of the following treatments:

• changes in medication
• lifestyle changes (including changes in eating and exercise habits)
• surgery
• physical therapy
• an alternative type-2 diabetes medication

Medications for Avandia® Side Effects

The precise type of medication(s) doctors prescribe for Avandia® side effects will depend on:

• the type and severity of an individual's Avandia® injuries
• an individual's medical history

Medications commonly prescribed to treat Avandia® side effects include:

• antibiotics
• anticoagulants (blood thinners)
• beta blockers
• diuretics

Legal Help Following Avandia® Injuries

After an injured Avandia® patient has received the treatment(s) he/she needs, it's also important that he consult with an experienced defective drug attorney to learn more about his/her legal rights.

During a free initial consultation, injured parties (including families of deceased Avandia® patients) can:

• Find out if they have a case against GlaxoSmithKline
• Learn more about the process associated with building and winning a defective drug lawsuit
• Get expert advice regarding the best manner in which to pursue their claim
• Secure aggressive, professional representation for future legal proceedings

Avandia® lawyers work on a contingency fee basis to encourage injured patients to seek the settlements they deserve.

For more information about Avandia® side effects, contact an Avandia lawyer today.

Additional Avandia® Side Effects Information

Avandia® was FDA approved in May 1999 for the treatment of type 2 diabetes. An oral agent, Avandia® is supposed to be used in addition to diet and exercise to improve blood sugar control. In March 2000, the Public Citizen consumer group petitioned the FDA for the immediate revision of "inadequate, misleading, and potentially dangerous professional product labeling" for the diabetes drugs referred to as "glitazones", which include Rezulin, Avandia® and Actos.

According to the consumer group, Avandia® and the other two glitazone drugs were approved as adjuncts to diet and exercise in order to improve blood sugar control in type 2 diabetes patients but the drug labeling was inadequate and did not mention safety and efficacy information that appeared relevant to all three drugs in the class. The failure to include the lack of efficacy compared to already available drugs, in addition to the deterioration of blood sugar levels when patients are switched from other anti-diabetic drugs to Avandia® was not mentioned.

Avandia® side effects, such as liver toxicity, heart function effects, weight gain, edema, anemia, low blood pressure, elevated lipid levels, and possible progesterone level changes were also nowhere to be found on Avandia® and other glitazone labelings. Rezulin was the first drug of the Avandia® inclusive class to be approved and was already banned in Great Britain at the time of the Public Citizen FDA petition. By 2000, Rezulin was recalled in the U.S. because of the instances of liver damage leading to death, necessity of liver transplants, and damage that occurred and has led to thousands of Rezulin lawsuits.

GlaxoSmithKline, Avandia®''s manufacturer, is currently investing $300 million for long-term Avandia® side effects studies. It can take years and years to better determine safety concerns beyond the FDA approval process because of the clinical trials that fail to show the overall effect a drug can have on a wider scope of patients. While many studies can involve a high number of people, it will still leave out many groups or not be able to show a drug risk that becomes more apparent as adverse event reports are made. In recent years, finding subjects is considered the number one obstacle in getting drug trials completed.

PPH, an uncommon clinical syndrome causing the blood pressure in the pulmonary artery to rise far above normal levels, is a difficult diagnosis of exclusion that has been linked to the use of some drugs. Due to the complexity of the rare lung disorder, it is often mistaken for other things. Avandia® side effects include edema, the buildup of fluid that can cause swelling in ankles or legs.

Commonly, PPH sufferers will show symptoms that often include edema. Since the PPH is commonly not diagnosed until it has progressed a long way and the side effects have become apparent, patients should be aware of Avandia® side effects that may be indicators of more serious conditions. Type 2 diabetes currently affects about 16 million Americans but the Avandia® side effects should be fully understood before choosing the treatment method. Avandia® is not appropriate for all patients and some Avandia® side effects can be significantly more prevalent in certain people.

"FDA Announces Avandia® Label Change"

The FDA announced that is has made a change regarding cardiovascular risks to the Avandia® (rosiglitazone) label and patient Medication Guide, Feb. 4, 2011.

The FDA announcement also said that Avandia®'s drug label was updated ...

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"Risk of Death Halts Government Study"

A government run diabetes trial was halted 18 months early after a safety analysis revealed an increased risk of death in patients whose blood sugar levels dipped too low.

The 10,000 patient trial was examining the effectiveness of aggressive ...

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"Journal of the American Medical Association reaffirms previous findings about the diabetes drug Avan"

A new study published in the Journal of the American Medical Association reaffirms previous findings about the diabetes drug Avandia—that is, it carries a significantly increased risk of heart failure, heart attack, and death.

Ob...

» Read More