AlloDerm Hernia Patch

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AlloDerm Hernia Patch

AlloDerm Tissue Matrix is a biological framework of donated human skin tissue harvested from cadavers. The cells of the matrix are removed from the skin's layers, the epidermis and dermis. Collagen is left behind. Because the tissue has no cells, it does not produce a rejection response in the recipient. Once purified, the collagen matrix can be transplanted into a person as a tissue graft that acts as a scaffold onto which human tissue cells can grow and multiply, thus enabling the person's own tissue to begin to regenerate.

The transplantation process works in the following way:

The AlloDerm material is transplanted into a patient's body where new tissue is needed to grow.
The components in AlloDerm act as foundation for new tissue regeneration. They contain the biological information that helps the patient's own tissue to grow into the graft.
Once the graft is in place, the patient's own blood cells migrate into the AlloDerm matrix.
Then, the patient's own tissue cells move into the AlloDerm and start the tissue regeneration process.
The process is the same as how our bodies replace cells during a cell turnover cycle.
As healing proceeds, more of a person's own cells move into the AlloDerm, and mend the wounded area, changing it into tissue that looks and functions naturally, according to LifeCell, the maker of AlloDerm.

LifeCell says that since its introduction in 1994, more than 750,000 AlloDerm grafts have been placed, without any case of transmission of disease.

AlloDerm was first used to treat burn victims' wounds. Today it is used to help repair gingiva in the mouth and help in healing of tissue after breast reconstruction following a mastectomy.

AlloDerm is also used to repair hernias.

AlloDerm and Hernia Surgery

A hernia occurs when there is a weakening of the abdominal wall, permitting the contents of the abdomen to protrude through the wall into areas where they do not belong. During surgery, the protruding contents are moved back into place. Then the AlloDerm mesh is used to strengthen and reinforce the area of weakness in the abdominal wall.

AlloDerm Repair Failures

The AlloDerm repair is not always successful. Complications of a hernia repair when AlloDerm has been used include:

Recurrent hernia and graft failure, requiring additional surgery
Tearing of the mesh
Perforations in the mesh
Erosion of the mesh
Infection
Abscess
Pain and soreness
Inflammation and swelling
Bruising and contusions
Adhesions